Skip to content

Cart

Your cart is empty

Continue shopping

Claim Your Welcome Gift

Receive a free gift with your first $45+ order

Claim Gift

Bundle & SAVE

Save on expertly curated skincare routines

Shop Now
Collection of Le Mieux skincare products on a neutral background with a person holding a serum dropper

Earn Rewards Points

Earn loyalty points with every purchase

Join Today

Free US Shipping

Free shipping with orders $45+

Shop Now

Featured products

EGF-DNA SerumWoman applying serum to her face with text about product benefits on a brown background
Sale price$115.00
Brightening CleanserBrightening Cleanser
Sale priceFrom $10.00
TGF-β Booster 1 oz amber bottle with black dropper lid isolated on a light grey background TGF-β Booster
Sale priceFrom $38.00
Le Mieux Bio Cell Rejuvenating Cream Jar white backgroundBio Cell Rejuvenating Cream
Sale price$48.00

Derma Relief Serum

Sale price$55.00
Size: 1 oz

This nutrient-rich, oil-based serum delivers essential lipids to replenish the skin’s natural barrier, relieve dryness, and restore balance.

Benefits icon Key Benefits
Soothe & Nourish Dry Skin
Targets icon Targets
Dryness & Inflammation
Derma Relief Serum 1 oz amber bottle with black dropper lid isolated on a light grey background
Derma Relief Serum1 oz Sale price$55.00

About this product

Details

An ultra-luxurious facial oil, packed with fast-absorbing, nutrient-rich botanicals to calm irritation and restore skin’s natural glow to dry, depleted skin. A potent blend of exotic oils—sacha inchi, bacaba, annatto, and açai—delivers essential lipids to soothe inflammation, minimize redness, and deeply nourish dry, flaking skin. The result? A soft, smooth, and resilient complexion that feels as good as it looks.

About Le Mieux: We only use the best so you can look your best. We’re redefining skincare by disrupting standard water-based formulas and prioritizing high concentrations of actives—no fillers, just purposeful ingredients that nourish deeply and promote your healthiest, best-looking skin yet.

How to use

After cleansing and toning, gently apply 3-5 drops onto face and neck in the morning and at night.

Tip: Mix with makeup foundation for easy application, blending, and an otherworldly glow!

Full Ingredient List

Argania Spinosa (Argan) Seed Oil, Plukenetia Volubilis (Sacha Inchi) Seed Oil, Bertholletia Excelsa (Brazil Nut) Seed Oil, Squalane, Avena Sativa (Oat) Oil, Ceramide AP, Bacaba Pulp Oil, Aleurites Moluccana (Kukui) Nut Oil, Bixa Orellana (Annatto) Seed Oil, Copaifera Officinalis (Balsam Copaiba) Oil, Macadamia Ternifolia Seed Oil, Glycine Soja (Soybean) Oil, Ceramide NP, Glycolipids, Phytosterols, Tocotrienol (Vitamin E), Euterpe Oleracea (Acai) Fruit Oil, Olea Europaea (Olive) Fruit Oil.

Key Ingredients

Our formulas showcase concentrated, premium ingredients that are thoughtfully curated and married to leading-edge growth factors, stem cells, and peptides.

Sacha Inchi Oil

Botanical oil that calms inflammation, irritation & dryness; improves barrier function.

Kukui Nut Oil

Botanical oil that helps relieve sensitivity & damage from environmental stressors.

Bacaba Pulp Oil

Botanical oil that helps to restore moisture in skin for improved elasticity.

Where this fits in your routine

Step 5: Serum

Applied after cleansing and before moisturizing, our serums deliver a concentrated dose of active ingredients to target specific skin concerns.

Free shipping

on all $45+ orders

Free Returns

within 30 days of purchase

Rewards Points

shop, earn, and redeem